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New insight into antiphospholipid syndrome: antibodies to β2glycoprotein I-domain 5 fail to induce thrombi in rats

Clinical studies have reported different diagnostic/predictive values of antibodies to domain 1 or 4/5 of β(2)glycoproteinI in terms of risk of thrombosis and pregnancy complications in patients with antiphospholipid syndrome. To obtain direct evidence for the pathogenic role of anti-domain 1 or ant...

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Detalhes bibliográficos
Publicado no:Haematologica
Main Authors: Durigutto, Paolo, Grossi, Claudia, Borghi, Maria Orietta, Macor, Paolo, Pregnolato, Francesca, Raschi, Elena, Myers, Michael P., de Groot, Philip G., Meroni, Pier Luigi, Tedesco, Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6442945/
https://ncbi.nlm.nih.gov/pubmed/30442725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2018.198119
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