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A Study of Collective Atomic Fluctuations and Cooperativity in a U1A-RNA Complex Based on Molecular Dynamics Simulations

Cooperative interactions play an important role in recognition and binding in macromolecular systems. In this study, we find that cross-correlated fluctuations can be used to identify cooperative networks in a protein-RNA system. The dynamics of the RRM-containing protein U1A–stem loop 2 RNA complex...

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Detalhes bibliográficos
Main Authors: Kormos, Bethany L., Baranger, Anne M., Beveridge, David L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1994251/
https://ncbi.nlm.nih.gov/pubmed/17194603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2006.10.022
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