CD28-independent induction of experimental autoimmune encephalomyelitis
Experimental autoimmune encephalomyelitis (EAE) is a T cell–mediated disease initiated by antigen-specific CD4(+) T cells. Signaling through CD28 is a critical second signal for activation of T cells, and CD28 knockout (CD28KO) mice have been reported to be resistant to induction of EAE. We now repo...
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| Veröffentlicht in: | J Clin Invest |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Clinical Investigation
2001
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC199425/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11238558/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI11220 |
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