A Camelid-Derived STAT-Specific Nanobody Inhibits Neuroinflammation and Ameliorates Experimental Autoimmune Encephalomyelitis (EAE)

Proinflammatory T-lymphocytes recruited into the brain and spinal cord mediate multiple sclerosis (MS) and currently there is no cure for MS. IFN-γ-producing Th1 cells induce ascending paralysis in the spinal cord while IL-17-producing Th17 cells mediate cerebellar ataxia. STAT1 and STAT3 are requir...

תיאור מלא

מידע ביבליוגרפי

Principais autores:	Evaristus C. Mbanefo, Allison Seifert, Manoj Kumar Yadav, Cheng-Rong Yu, Vijayaraj Nagarajan, Ashutosh Parihar, Sunanda Singh, Charles E. Egwuagu
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	MDPI AG 2024-06-01
סדרה:	Cells
נושאים:	nanobody SBT-100 encephalomyelitis EAE autoimmunity STAT1
גישה מקוונת:	https://www.mdpi.com/2073-4409/13/12/1042
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!