Heat Shock Protein 90 Inhibitors Prolong Survival, Attenuate Inflammation, and Reduce Lung Injury in Murine Sepsis

Rationale: Severe sepsis is the leading cause of death for patients in intensive care units. Patients with severe sepsis develop multiple organ failure, including acute lung injury (ALI), resulting from a deregulated inflammatory response. Inhibitors of the ubiquitous chaperone, heat shock protein 9...

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Detalhes bibliográficos
Main Authors: Chatterjee, Anuran, Dimitropoulou, Christiana, Drakopanayiotakis, Fotios, Antonova, Galina, Snead, Connie, Cannon, Joseph, Venema, Richard C., Catravas, John D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2007
Assuntos:
B. Critical Care
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1994236/
https://ncbi.nlm.nih.gov/pubmed/17615388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200702-291OC
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