Central Role of Muc5ac Expression in Mucous Metaplasia and Its Regulation by Conserved 5′ Elements

Mucus hypersecretion contributes to morbidity and mortality in many obstructive lung diseases. Gel-forming mucins are the chief glycoprotein components of airway mucus, and elevated expression of these during mucous metaplasia precedes the hypersecretory phenotype. Five orthologous genes (MUC2, MUC5...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Young, Hays W. J., Williams, Olatunji W., Chandra, Divay, Bellinghausen, Lindsey K., Pérez, Guillermina, Suárez, Alberto, Tuvim, Michael J., Roy, Michelle G., Alexander, Samantha N., Moghaddam, Seyed J., Adachi, Roberto, Blackburn, Michael R., Dickey, Burton F., Evans, Christopher M.
Format: Artigo
Langue:Inglês
Publié: American Thoracic Society 2007
Sujets:
Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1994232/
https://ncbi.nlm.nih.gov/pubmed/17463395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2005-0460OC
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires