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Central Role of Muc5ac Expression in Mucous Metaplasia and Its Regulation by Conserved 5′ Elements
Mucus hypersecretion contributes to morbidity and mortality in many obstructive lung diseases. Gel-forming mucins are the chief glycoprotein components of airway mucus, and elevated expression of these during mucous metaplasia precedes the hypersecretory phenotype. Five orthologous genes (MUC2, MUC5...
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| Auteurs principaux: | , , , , , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Thoracic Society
2007
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1994232/ https://ncbi.nlm.nih.gov/pubmed/17463395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2005-0460OC |
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