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Muc5ac null mice are predisposed to spontaneous gastric antro-pyloric hyperplasia and adenomas coupled with attenuated H. pylori induced corpus mucous metaplasia

Gastric cancer (GC) is the third leading cause of cancer-related deaths worldwide and is strongly associated with chronic Helicobacter pylori (Hp) infection. The ability of Hp to closely adhere to the gastric surface protective mucous layer containing mucins (MUC in humans and Muc in animals), prima...

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Detalhes bibliográficos
Publicado no:Lab Invest
Main Authors: Muthupalani, Sureshkumar, Ge, Zhongming, Joy, Joanna, Feng, Yan, Dobey, Carrie, Cho, Hye-Youn, Langenbach, Robert, Wang, Timothy C, Hagen, Susan J, Fox, James G
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6927550/
https://ncbi.nlm.nih.gov/pubmed/31399638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41374-019-0293-y
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