Recruitment of SH2-containing protein tyrosine phosphatase SHP-1 to the interleukin 2 receptor; loss of SHP-1 expression in human T-lymphotropic virus type I-transformed T cells

Interleukin 2 (IL-2) rapidly induces tyrosine phosphorylation of intracellular substrates, including the IL-2 receptor β chain (IL-2Rβ), Janus kinase 1 (Jak1), Jak3, signal transducer/activator of transcription proteins, and Shc, but the mechanism underlying dephosphorylation of these proteins is no...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Migone, Thi-Sau, Cacalano, Nicholas A., Taylor, Naomi, Yi, Taolin, Waldmann, Thomas A., Johnston, James A.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1998
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19925/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9520455/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.7.3845
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