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Recruitment of SH2-containing protein tyrosine phosphatase SHP-1 to the interleukin 2 receptor; loss of SHP-1 expression in human T-lymphotropic virus type I-transformed T cells

Interleukin 2 (IL-2) rapidly induces tyrosine phosphorylation of intracellular substrates, including the IL-2 receptor β chain (IL-2Rβ), Janus kinase 1 (Jak1), Jak3, signal transducer/activator of transcription proteins, and Shc, but the mechanism underlying dephosphorylation of these proteins is no...

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Bibliographische Detailangaben
Hauptverfasser: Migone, Thi-Sau, Cacalano, Nicholas A., Taylor, Naomi, Yi, Taolin, Waldmann, Thomas A., Johnston, James A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 1998
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC19925/
https://ncbi.nlm.nih.gov/pubmed/9520455
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