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Crystal Structure and Allosteric Regulation of the Cytoplasmic Escherichia coli L-Asparaginase I

AnsA is the cytoplasmic asparaginase from Escherichia coli involved in intracellular asparagine utilization. Analytical ultracentifugation and X-ray crystallography reveal that AnsA forms a tetrameric structure as a dimer of two intimate dimers. Kinetic analysis of the enzyme reveals that AnsA is po...

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Bibliografske podrobnosti
Main Authors: Yun, Mi-Kyung, Nourse, Amanda, White, Stephen W., Rock, Charles O., Heath, Richard J.
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1991333/
https://ncbi.nlm.nih.gov/pubmed/17451745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.03.061
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