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QUANTUM MECHANICAL CALCULATIONS OF CHARGE EFFECTS ON GATING THE KcsA CHANNEL

A series of ab initio (density functional) calculations were carried out on side chains of a set of amino acids, plus water, from the (intracellular) gating region of the KcsA K(+) channel. Their atomic coordinates, except hydrogen, are known from X-ray structures[1–3], as are the coordinates of som...

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Autori principali: Kariev, Alisher M., Znamenskiy, Vasiliy S., Green, Michael E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1989151/
https://ncbi.nlm.nih.gov/pubmed/17336921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2007.01.021
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