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The Open Gate of the KV1.2 Channel: Quantum Calculations Show the Key Role of Hydration
The open gate of the K(v)1.2 voltage-gated potassium channel can just hold a hydrated K(+) ion. Quantum calculations starting from the x-ray coordinates of the channel confirm this, showing little change from the x-ray coordinates for the protein. Water molecules not in the x-ray coordinates, and th...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Biophysical Society
2014
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3945100/ https://ncbi.nlm.nih.gov/pubmed/24507595 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.11.4495 |
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