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Tissue factor: a link between C5a and neutrophil activation in antiphospholipid antibody–induced fetal injury

Fetal loss in patients with antiphospholipid (aPL) antibodies has been ascribed to thrombosis of placental vessels. However, we have shown that inflammation, specifically activation of complement with generation of the anaphylotoxin C5a, is an essential trigger of fetal injury. In this study, we ana...

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Главные авторы: Redecha, Patricia, Tilley, Rachel, Tencati, Michael, Salmon, Jane E., Kirchhofer, Daniel, Mackman, Nigel, Girardi, Guillermina
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Hematology 2007
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1988945/
https://ncbi.nlm.nih.gov/pubmed/17536017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-01-070631
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