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Tissue factor: a link between C5a and neutrophil activation in antiphospholipid antibody–induced fetal injury

Fetal loss in patients with antiphospholipid (aPL) antibodies has been ascribed to thrombosis of placental vessels. However, we have shown that inflammation, specifically activation of complement with generation of the anaphylotoxin C5a, is an essential trigger of fetal injury. In this study, we ana...

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Detalhes bibliográficos
Main Authors: Redecha, Patricia, Tilley, Rachel, Tencati, Michael, Salmon, Jane E., Kirchhofer, Daniel, Mackman, Nigel, Girardi, Guillermina
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1988945/
https://ncbi.nlm.nih.gov/pubmed/17536017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-01-070631
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