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Tissue factor: a link between C5a and neutrophil activation in antiphospholipid antibody–induced fetal injury

Fetal loss in patients with antiphospholipid (aPL) antibodies has been ascribed to thrombosis of placental vessels. However, we have shown that inflammation, specifically activation of complement with generation of the anaphylotoxin C5a, is an essential trigger of fetal injury. In this study, we ana...

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Bibliografske podrobnosti
Main Authors: Redecha, Patricia, Tilley, Rachel, Tencati, Michael, Salmon, Jane E., Kirchhofer, Daniel, Mackman, Nigel, Girardi, Guillermina
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1988945/
https://ncbi.nlm.nih.gov/pubmed/17536017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-01-070631
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