Role of tissue factor in a mouse model of thrombotic microangiopathy induced by antiphospholipid antibodies

Using different mouse monoclonal and human antiphospholipid (aPL) antibodies, we developed a new animal model of renal injury that shares many features with thrombotic microangiopathy (TMA). We found that more than 1 mechanism/signaling pathway is involved in glomerular injury induced by aPL antibod...

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Detalhes bibliográficos
Main Authors: Seshan, Surya V., Franzke, Claus-Werner, Redecha, Patricia, Monestier, Marc, Mackman, Nigel, Girardi, Guillermina
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
Assuntos:
Thrombosis and Hemostasis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2927091/
https://ncbi.nlm.nih.gov/pubmed/19535796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-01-199117
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