Complement C5a receptors and neutrophils mediate fetal injury in the antiphospholipid syndrome

Antiphospholipid syndrome (APS) is defined by recurrent pregnancy loss and thrombosis in the presence of antiphospholipid (aPL) Ab’s. Currently, therapy for pregnant women with APS is focused on preventing thrombosis, but anticoagulation is only partially successful in averting miscarriage. We hypot...

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Main Authors: Girardi, Guillermina, Berman, Jessica, Redecha, Patricia, Spruce, Lynn, Thurman, Joshua M., Kraus, Damian, Hollmann, Travis J., Casali, Paolo, Caroll, Michael C., Wetsel, Rick A., Lambris, John D., Holers, V. Michael, Salmon, Jane E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2003
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC281643/
https://ncbi.nlm.nih.gov/pubmed/14660741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200318817
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