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Cdc42 acts downstream of Bazooka to regulate neuroblast polarity through Par-6/aPKC
Cdc42 recruits Par-6/aPKC to establish cell polarity from worms to mammals. Although Cdc42 is reported to have no function in Drosophila neuroblasts, a model for cell polarity and asymmetric cell division, we show that Cdc42 colocalizes with Par-6/aPKC at the apical cortex in a Bazooka-dependent man...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2007
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1988841/ https://ncbi.nlm.nih.gov/pubmed/17726059 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.014902 |
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