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Twins/PP2A regulates aPKC to control neuroblast cell polarity and self-renewal

Asymmetric cell division is a mechanism for generating cell diversity as well as maintaining stem cell homeostasis in both Drosophila and mammals. In Drosophila, larval neuroblasts are stem cell-like progenitors that divide asymmetrically to generate neurons of the adult brain. Mitotic neuroblasts l...

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Detalhes bibliográficos
Main Authors: Chabu, Chiswili, Doe, Chris Q.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728501/
https://ncbi.nlm.nih.gov/pubmed/19374896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2009.04.014
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