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Dap160/intersectin binds and activates aPKC to regulate cell polarity and cell cycle progression
The atypical protein kinase C (aPKC) is required for cell polarization of many cell types, and is upregulated in several human tumors. Despite its importance in cell polarity and growth control, relatively little is known about how aPKC activity is regulated. Here, we use a biochemical approach to i...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2683763/ https://ncbi.nlm.nih.gov/pubmed/18614576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.024059 |
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