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The Cdc42/Par6/aPKC polarity complex regulates apoptosis-induced compensatory proliferation in epithelia

BACKGROUND: In response to stress- or tissue damage-induced apoptosis, unaffected epithelial cells undergo compensatory proliferation to maintain the integrity of the epithelium. Proximal signals regulating this response are not fully appreciated, but JNK activity appears to be critical for both apo...

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Autori principali: Warner, Stephen J., Yashiro, Hanako, Longmore, Gregory D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910247/
https://ncbi.nlm.nih.gov/pubmed/20381350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2010.03.025
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