Increased atherosclerosis in LDL receptor–null mice lacking ACAT1 in macrophages

During atherogenesis, circulating macrophages migrate into the subendothelial space, internalize cholesterol-rich lipoproteins, and become foam cells by progressively accumulating cholesterol esters. The inhibition of macrophage acyl coenzyme A:cholesterol acyltransferase (ACAT), which catalyzes the...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Fazio, Sergio, Major, Amy S., Swift, Larry L., Gleaves, Linda A., Accad, Michel, Linton, MacRae F., Farese, Robert V.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2001
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC198874/
https://ncbi.nlm.nih.gov/pubmed/11160132
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