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Prediction of individual genetic risk to disease from genome-wide association studies
Empirical studies suggest that the effect sizes of individual causal risk alleles underlying complex genetic diseases are small, with most genotype relative risks in the range of 1.1–2.0. Although the increased risk of disease for a carrier is small for any single locus, knowledge of multiple-risk a...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1987352/ https://ncbi.nlm.nih.gov/pubmed/17785532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.6665407 |
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