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Prediction of individual genetic risk to disease from genome-wide association studies

Empirical studies suggest that the effect sizes of individual causal risk alleles underlying complex genetic diseases are small, with most genotype relative risks in the range of 1.1–2.0. Although the increased risk of disease for a carrier is small for any single locus, knowledge of multiple-risk a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wray, Naomi R., Goddard, Michael E., Visscher, Peter M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2007
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1987352/
https://ncbi.nlm.nih.gov/pubmed/17785532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.6665407
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