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Novel Genetic Analysis for Case-Control Genome-Wide Association Studies: Quantification of Power and Genomic Prediction Accuracy

Genome-wide association studies (GWAS) are routinely conducted for both quantitative and binary (disease) traits. We present two analytical tools for use in the experimental design of GWAS. Firstly, we present power calculations quantifying power in a unified framework for a range of scenarios. In t...

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Detaylı Bibliyografya
Asıl Yazarlar: Lee, Sang Hong, Wray, Naomi R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3747270/
https://ncbi.nlm.nih.gov/pubmed/23977056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071494
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