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Novel Genetic Analysis for Case-Control Genome-Wide Association Studies: Quantification of Power and Genomic Prediction Accuracy

Genome-wide association studies (GWAS) are routinely conducted for both quantitative and binary (disease) traits. We present two analytical tools for use in the experimental design of GWAS. Firstly, we present power calculations quantifying power in a unified framework for a range of scenarios. In t...

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Detalles Bibliográficos
Autores principales: Lee, Sang Hong, Wray, Naomi R.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3747270/
https://ncbi.nlm.nih.gov/pubmed/23977056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071494
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