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Impact of diagnostic misclassification on estimation of genetic correlations using genome-wide genotypes

Disorders that share genetic risk factors often are placed in closely related diagnostic categories and treated similarly. Until recently, evidence for shared genetic etiology derived from classical research strategies – coaggregation in family and twin studies. Accumulating sufficient numbers of fa...

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Detalhes bibliográficos
Main Authors: Wray, Naomi R, Lee, Sang Hong, Kendler, Kenneth S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355255/
https://ncbi.nlm.nih.gov/pubmed/22258521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2011.257
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