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Estimating Missing Heritability for Disease from Genome-wide Association Studies
Genome-wide association studies are designed to discover SNPs that are associated with a complex trait. Employing strict significance thresholds when testing individual SNPs avoids false positives at the expense of increasing false negatives. Recently, we developed a method for quantitative traits t...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Elsevier
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3059431/ https://ncbi.nlm.nih.gov/pubmed/21376301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2011.02.002 |
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