Central Leptin Gene Therapy Corrects Skeletal Abnormalities in Leptin-deficient ob/ob Mice

Skeletal growth is tightly coupled to energy balance via complex and incompletely understood mechanisms. Leptin-deficient ob/ob mice are obese and develop multiple pathologies associated with the metabolic syndrome. Additionally, ob/ob mice have skeletal abnormalities. The objective of this study wa...

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Detaylı Bibliyografya
Asıl Yazarlar: Iwaniec, Urszula T., Boghossian, Stéphane, Lapke, Paul D., Turner, Russell T., Kalra, Satya P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2007
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1986832/
https://ncbi.nlm.nih.gov/pubmed/17346852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2007.02.001
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