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DBC2 Resistance is Achieved by Enhancing 26S Proteasome-mediated Protein Degradation

Tumor suppressor gene DBC2 stops growth of tumor cells through regulation of CCND1. Interference of CCND1 down-regulation prevented growth arrest caused by DBC2 [1]. It was also noted that DBC2 resistant cells eventually arose after repeated induction of DBC2 with muristerone A treatment [2]. In ord...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Collado, Denise, Yoshihara, Takashi, Hamaguchi, Masaaki
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1986727/
https://ncbi.nlm.nih.gov/pubmed/17617377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2007.06.127
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