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Regulatory functions of CD8(+)CD28(–) T cells in an autoimmune disease model
CD8(+) T cell depletion renders CD28-deficient mice susceptible to experimental autoimmune encephalomyelitis (EAE). In addition, CD8(–/–)CD28(–/–) double-knockout mice are susceptible to EAE. These findings suggest a role for CD8(+) T cells in the resistance of CD28-deficient mice to disease. Adopti...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Clinical Investigation
2003
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC198520/ https://ncbi.nlm.nih.gov/pubmed/14523041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200317935 |
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