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Effect of targeted disruption of STAT4 and STAT6 on the induction of experimental autoimmune encephalomyelitis

Experimental autoimmune encephalomyelitis (EAE) is mediated by myelin-specific CD4(+) T cells secreting Th1 cytokines, while recovery from disease is associated with expression of Th2 cytokines. Investigations into the role of individual cytokines in disease induction have yielded contradictory resu...

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Detalhes bibliográficos
Main Authors: Chitnis, Tanuja, Najafian, Nader, Benou, Christina, Salama, Alan D., Grusby, Michael J., Sayegh, Mohamed H., Khoury, Samia J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC209380/
https://ncbi.nlm.nih.gov/pubmed/11544280
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