Regulation of DNA damage-induced apoptosis by the c-Abl tyrosine kinase

Activation of the c-Abl protein tyrosine kinase by certain DNA-damaging agents contributes to down-regulation of Cdk2 and G(1) arrest by a p53-dependent mechanism. The present work investigates the potential role of c-Abl in apoptosis induced by DNA damage. Transient transfection studies with wild-t...

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Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Yuan, Zhi-Min, Huang, Yinyin, Ishiko, Takatoshi, Kharbanda, Surender, Weichselbaum, Ralph, Kufe, Donald
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 1997
Matèries:	Biological Sciences
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19809/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9037071/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.4.1437
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