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A genetic system to identify DNA polymerase β mutator mutants

DNA polymerase β (pol β) is a 39-kDa protein that functions in DNA repair processes in mammalian cells. As a first step toward understanding mechanisms of polymerase fidelity, we developed a genetic method to identify mammalian pol β mutator mutants. This screen takes advantage of a microbial geneti...

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Sparad:
I publikationen:Proc Natl Acad Sci U S A
Huvudupphov: Washington, Stacy L., Yoon, Margaret S., Chagovetz, Alexander M., Li, Shu-Xia, Clairmont, Caroline A., Preston, Bradley D., Eckert, Kristin A., Sweasy, Joann B.
Materialtyp: Artigo
Språk:Inglês
Utgiven: National Academy of Sciences 1997
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19789/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9037051/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.4.1321
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