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The Tyr-265-to-Cys mutator mutant of DNA polymerase β induces a mutator phenotype in mouse LN12 cells

DNA polymerase β functions in both base excision repair and meiosis. Errors committed by polymerase β during these processes could result in mutations. Using a complementation system, in which rat DNA polymerase β substitutes for DNA polymerase I of Escherichia coli, we previously isolated a DNA pol...

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Bibliografiske detaljer
Main Authors: Clairmont, Caroline A., Narayanan, Latha, Sun, Ka-Wai, Glazer, Peter M., Sweasy, Joann B.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 1999
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC22251/
https://ncbi.nlm.nih.gov/pubmed/10449735
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