The Tyr-265-to-Cys mutator mutant of DNA polymerase β induces a mutator phenotype in mouse LN12 cells

DNA polymerase β functions in both base excision repair and meiosis. Errors committed by polymerase β during these processes could result in mutations. Using a complementation system, in which rat DNA polymerase β substitutes for DNA polymerase I of Escherichia coli, we previously isolated a DNA pol...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Clairmont, Caroline A., Narayanan, Latha, Sun, Ka-Wai, Glazer, Peter M., Sweasy, Joann B.
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1999
Sujets:	Biological Sciences
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22251/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10449735/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.17.9580
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