A genetic system to identify DNA polymerase β mutator mutants

DNA polymerase β (pol β) is a 39-kDa protein that functions in DNA repair processes in mammalian cells. As a first step toward understanding mechanisms of polymerase fidelity, we developed a genetic method to identify mammalian pol β mutator mutants. This screen takes advantage of a microbial geneti...

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Bibliografiske detaljer
Main Authors: Washington, Stacy L., Yoon, Margaret S., Chagovetz, Alexander M., Li, Shu-Xia, Clairmont, Caroline A., Preston, Bradley D., Eckert, Kristin A., Sweasy, Joann B.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences of the USA 1997
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC19789/
https://ncbi.nlm.nih.gov/pubmed/9037051
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