A genetic system to identify DNA polymerase β mutator mutants
DNA polymerase β (pol β) is a 39-kDa protein that functions in DNA repair processes in mammalian cells. As a first step toward understanding mechanisms of polymerase fidelity, we developed a genetic method to identify mammalian pol β mutator mutants. This screen takes advantage of a microbial geneti...
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| Опубликовано в:: | Proc Natl Acad Sci U S A |
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| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
1997
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19789/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9037051/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.4.1321 |
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