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Heme oxygenase/carbon monoxide-biliverdin pathway down regulates neutrophil rolling, adhesion and migration in acute inflammation

BACKGROUND AND PURPOSE: Heme oxygenase (HO) activity is known to down-regulate inflammatory events. Here, we address the role of HO and its metabolites, carbon monoxide (CO) and biliverdin (BVD), in leukocyte rolling, adhesion and neutrophil migration during inflammatory processes. EXPERIMENTAL APPR...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Freitas, A, Alves-Filho, J C, Secco, D D, Neto, A F, Ferreira, S H, Barja-Fidalgo, C, Cunha, F Q
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1978436/
https://ncbi.nlm.nih.gov/pubmed/16953189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706882
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