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Heme oxygenase/carbon monoxide-biliverdin pathway down regulates neutrophil rolling, adhesion and migration in acute inflammation

BACKGROUND AND PURPOSE: Heme oxygenase (HO) activity is known to down-regulate inflammatory events. Here, we address the role of HO and its metabolites, carbon monoxide (CO) and biliverdin (BVD), in leukocyte rolling, adhesion and neutrophil migration during inflammatory processes. EXPERIMENTAL APPR...

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Detalhes bibliográficos
Main Authors: Freitas, A, Alves-Filho, J C, Secco, D D, Neto, A F, Ferreira, S H, Barja-Fidalgo, C, Cunha, F Q
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1978436/
https://ncbi.nlm.nih.gov/pubmed/16953189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706882
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