Cellular effects and metabolic stability of N1-cyclic inosine diphosphoribose and its derivatives

BACKGROUND AND PURPOSE: Recently, a number of mimics of the second messenger cyclic ADP-ribose (cADPR) with replacement of adenosine by inosine were introduced. In addition, various alterations in the molecule ranging from substitutions at C8 of the base up to full replacement of the ribose moieties...

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Main Authors: Kirchberger, T, Wagner, G, Xu, J, Cordiglieri, C, Wang, P, Gasser, A, Fliegert, R, Bruhn, S, Flügel, A, Lund, F E, Zhang, L-h, Potter, B V L, Guse, A H
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2006
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Research Papers
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1978434/
https://ncbi.nlm.nih.gov/pubmed/16967053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706869
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