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Crystallization and diffraction properties of the Fab fragment of 3B5H10, an antibody specific for disease-causing polyglutamine stretches

Because it binds soluble forms of proteins with disease-associated polyglutamine expansions, the antibody 3B5H10 is a powerful tool for studying polyglutamine-related diseases. Crystals of the 3B5H10 Fab (47 kDa) were obtained by vapor diffusion at room temperature from PEG 3350. However, the initia...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Peters-Libeu, Clare, Newhouse, Yvonne, Krishnan, Preethi, Cheung, Kenneth, Brooks, Elizabeth, Weisgraber, Karl, Finkbeiner, Steven
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: International Union of Crystallography 2005
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1978161/
https://ncbi.nlm.nih.gov/pubmed/16511236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309105036547
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