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Spectroscopic validation of the pentameric structure of phospholamban

Phospholamban (PLN) regulates calcium translocation within cardiac myocytes by shifting sarco(endo)plasmic reticulum Ca(2+)-ATPase (SERCA) affinity for calcium. Although the monomeric form of PLN (6 kDa) is the principal inhibitory species, recent evidence suggests that the PLN pentamer (30 kDa) als...

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Autors principals: Traaseth, Nathaniel J., Verardi, Raffaello, Torgersen, Kurt D., Karim, Christine B., Thomas, David D., Veglia, Gianluigi
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1976191/
https://ncbi.nlm.nih.gov/pubmed/17804809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0701016104
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