Prostaglandins PGE(2) and PGI(2) promote endothelial barrier enhancement via PKA- and Epac1/Rap1-dependent Rac activation

Prostaglandin E(2) (PGE(2)) and prostacyclin are lipid mediators produced by cyclooxygenase and implicated in the regulation of vascular function, wound repair, inflammatory processes, and acute lung injury. Although protective effects of these prostaglandins (PGs) are associated with stimulation of...

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Bibliografiske detaljer
Main Authors: Birukova, Anna A., Zagranichnaya, Tatiana, Fu, Panfeng, Alekseeva, Elena, Chen, Weiguo, Jacobson, Jeffrey R., Birukov, Konstantin G.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1974901/
https://ncbi.nlm.nih.gov/pubmed/17493609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2007.03.036
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