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Cytokine-dependent imatinib resistance in mouse BCR-ABL(+), Arf-null lymphoblastic leukemia

Retroviral transduction of the BCR-ABL kinase into primary mouse bone marrow cells lacking the Arf tumor suppressor rapidly generates polyclonal populations of continuously self-renewing pre-B cells, virtually all of which have leukemic potential. Intravenous infusion of 20 such cells into healthy s...

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Bibliografische gegevens
Hoofdauteurs: Williams, Richard T., den Besten, Willem, Sherr, Charles J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 2007
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1973142/
https://ncbi.nlm.nih.gov/pubmed/17761812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1588607
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