A phase I and pharmacokinetic study of intraperitoneal carboplatin and etoposide.

BACKGROUND: We attempted to determine the maximum tolerated dose and toxicity of etoposide (VP-16) when administered in combination with carboplatin (CBDCA) (300 mg m-2) and administered via the intraperitoneal (IP) route. METHODS AND MATERIALS: A total of 26 patients were treated on this trial. CBD...

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Main Authors: McClay, E. F., Goel, R., Andrews, P., Gorelick, S., Kirmani, S., Kim, S., Braly, P., Plaxe, S., Hoff, S., Alcaraz, J.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1993
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1968622/
https://ncbi.nlm.nih.gov/pubmed/8398708
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