A phase I and pharmacokinetic study of indisulam in combination with carboplatin

Indisulam (E7070) is an anticancer agent that is currently being evaluated in phase II clinical studies. A significant reduction in glutathione synthetase and glutathione reductase transcripts by indisulam provided a molecular basis for its combination with platinum agents. Indisulam demonstrated hi...

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Bibliografske podrobnosti
Main Authors: Dittrich, C, Zandvliet, A S, Gneist, M, Huitema, A D R, King, A A J, Wanders, J
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2007
Teme:
Clinical Study
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2360043/
https://ncbi.nlm.nih.gov/pubmed/17285128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603606
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