Phase I Trial of Carboplatin and Etoposide in Combination with Panobinostat in Patients with Lung Cancer

A phase I trial consisting of panobinostat (a HDAC inhibitor), carboplatin and etoposide was condacted in patients with lung cancer. Patients and Methods: Patients received carboplatin AUC5 on day 1 and etoposide 100 mg/m(2) on days 1, 2 and 3, every 21 days. Concurrent oral panobinostat was given 3...

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Main Authors: TARHINI, AHMAD A., ZAHOOR, HARIS, MCLAUGHLIN, BRIAN, GOODING, WILLIAM E., SCHMITZ, JOHN C., SIEGFRIED, JILL M., SOCINSKI, MARK A., ARGIRIS, ATHANASSIOS
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4157617/
https://ncbi.nlm.nih.gov/pubmed/24123018
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