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The entry of entry inhibitors: A fusion of science and medicine

For HIV-1 to enter a cell, its envelope protein (Env) must sequentially engage CD4 and a chemokine coreceptor, triggering conformational changes in Env that ultimately lead to fusion between the viral and host cell membranes. Each step of the virus entry pathway is a potential target for novel antiv...

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Autori principali: Moore, John P., Doms, Robert W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC196849/
https://ncbi.nlm.nih.gov/pubmed/12960367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1932511100
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