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The entry of entry inhibitors: A fusion of science and medicine
For HIV-1 to enter a cell, its envelope protein (Env) must sequentially engage CD4 and a chemokine coreceptor, triggering conformational changes in Env that ultimately lead to fusion between the viral and host cell membranes. Each step of the virus entry pathway is a potential target for novel antiv...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2003
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC196849/ https://ncbi.nlm.nih.gov/pubmed/12960367 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1932511100 |
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