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Selectivity and proofreading both contribute significantly to the fidelity of RNA polymerase III transcription
We examine here the mechanisms ensuring the fidelity of RNA synthesis by RNA polymerase III (Pol III). Misincorporation could only be observed by using variants of Pol III deficient in the intrinsic RNA cleavage activity. Determination of relative rates of the reactions producing correct and erroneo...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1965525/ https://ncbi.nlm.nih.gov/pubmed/17553959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0704116104 |
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