Deletion of Ultraconserved Elements Yields Viable Mice

Ultraconserved elements have been suggested to retain extended perfect sequence identity between the human, mouse, and rat genomes due to essential functional properties. To investigate the necessities of these elements in vivo, we removed four noncoding ultraconserved elements (ranging in length fr...

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Bibliografiske detaljer
Main Authors: Ahituv, Nadav, Zhu, Yiwen, Visel, Axel, Holt, Amy, Afzal, Veena, Pennacchio, Len A, Rubin, Edward M
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2007
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1964772/
https://ncbi.nlm.nih.gov/pubmed/17803355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0050234
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