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Functional Autonomy of Distant-Acting Human Enhancers

Many human genes are associated with dispersed arrays of transcriptional enhancers that regulate their expression in time and space. Studies in invertebrate model systems have suggested that these elements could function as discrete and independent regulatory units, but the in vivo combinatorial pro...

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Detalhes bibliográficos
Main Authors: Visel, Axel, Akiyama, Jennifer A., Shoukry, Malak, Afzal, Veena, Rubin, Edward M., Pennacchio, Len A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683195/
https://ncbi.nlm.nih.gov/pubmed/19268701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygeno.2009.02.002
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