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Targeted Deletion of the 9p21 Noncoding Coronary Artery Disease Risk Interval in Mice
Sequence polymorphisms in a 58kb interval on chromosome 9p21 confer a markedly increased risk for coronary artery disease (CAD), the leading cause of death worldwide 1,2. The variants have a substantial impact on the epidemiology of CAD and other life-threatening vascular conditions since nearly a q...
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| Auteurs principaux: | , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2938076/ https://ncbi.nlm.nih.gov/pubmed/20173736 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08801 |
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